wqspt - Permutation Test for Weighted Quantile Sum Regression
Implements a permutation test method for the weighted
quantile sum (WQS) regression, building off the 'gWQS' package
(Renzetti et al. <https://CRAN.R-project.org/package=gWQS>).
Weighted quantile sum regression is a statistical technique to
evaluate the effect of complex exposure mixtures on an outcome
(Carrico et al. 2015 <doi:10.1007/s13253-014-0180-3>). The
model features a statistical power and Type I error (i.e.,
false positive) rate trade-off, as there is a machine learning
step to determine the weights that optimize the linear model
fit. This package provides an alternative method based on a
permutation test that should reliably allow for both high power
and low false positive rate when utilizing WQS regression (Day
et al. 2022 <doi:10.1289/EHP10570>).